Syn-AKE · Dipeptide diaminobutyroyl benzylamide diacetate

What it is

Syn-AKE was designed to mimic waglerin-1, a peptide in the venom of the temple viper. It is a dipeptide-like molecule, not a natural sequence.

What researchers study

Reversible antagonist at the muscle-type nicotinic acetylcholine receptor.
Studied in cosmetic research on expression lines.

Specifications

Sequence	`H-βAla-Pro-Dab-NHBn · 2 CH3COOH`Dab is 2,4-diaminobutyric acid; NHBn is a benzylamide. Supplied as the diacetate salt.
Molecular formula	C₂₃H₃₇N₅O₇
Molecular weight	495.6 g/mol
PubChem	CID 71465152
Form	Lyophilized powder
Vial sizes	200 mg
Storage	Unopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

Purity by reversed-phase HPLC: the main peak's share of the total peak area.
Identity by mass spectrometry: the observed mass should match the expected 495.6 g/mol.
Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.