Triptorelin · GnRH analog

What it is

Triptorelin is GnRH with D-Trp in place of glycine at position 6. The change slows breakdown and strengthens receptor binding.

What researchers study

Agonist at the GnRH receptor.
Continuous exposure desensitizes the receptor and suppresses LH and FSH. Reproductive-endocrinology research uses this effect.

Specifications

Sequence	`pGlu-HWSY-(D-Trp)-LRPG-NH2`
Molecular formula	C₆₄H₈₂N₁₈O₁₃
Molecular weight	1311.4 g/mol
PubChem	CID 25074470
Form	Lyophilized powder
Vial sizes	2 mg
Storage	Unopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

Purity by reversed-phase HPLC: the main peak's share of the total peak area.
Identity by mass spectrometry: the observed mass should match the expected 1311.4 g/mol.
Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.