What it is
ARA-290 (cibinetide) copies the helix B surface of erythropoietin (EPO). That surface engages a tissue-protective receptor, not the receptor that drives red blood cell production.
What researchers study
- Binds the innate repair receptor, a complex of the EPO receptor and CD131.
- Studied in models of nerve injury and inflammation without the blood-cell effects of EPO.
Specifications
| Sequence | pGlu-EQLERALNSS |
| Molecular formula | C51H84N16O21 |
| Molecular weight | 1257.3 g/mol |
| PubChem | CID 91810664 |
| Form | Lyophilized powder |
| Vial sizes | 16 mg |
| Storage | Unopened: 2 to 8 °C, away from light |
How each lot is tested
Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:
- Purity by reversed-phase HPLC: the main peak's share of the total peak area.
- Identity by mass spectrometry: the observed mass should match the expected 1257.3 g/mol.
- Endotoxin, measured for every lot.
The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.
The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.
Storage and handling
Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.
For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.