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Thymosin α1

Thymalfasin

A 28-residue acetylated peptide first isolated from calf thymus.

Vial size

Thymic and antimicrobialHPLC · MS · Endotoxin

Thymosin α1 2 mg research vial

What it is

Thymosin α1 was first isolated in the 1970s from thymosin fraction 5, a calf thymus extract. The synthetic peptide matches the natural N-acetylated sequence.

What researchers study

  • Studied in immunology research on T-cell maturation.
  • Research also looks at its signaling through Toll-like receptors in dendritic cells.

Specifications

SequenceAc-SDAAVDTSSEITTKDLKEKKEVVEEAEN
Molecular formulaC129H215N33O55
Molecular weight3108.3 g/mol
PubChemCID 16130571
FormLyophilized powder
Vial sizes2 mg, 5 mg, 15 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 3108.3 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.