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Astressin-B

CRF receptor antagonist

A long-acting antagonist of corticotropin-releasing factor receptors.

Vial size

Hypothalamic and pituitaryHPLC · MS · Endotoxin

Astressin-B 2 mg research vial

What it is

Astressin-B is a synthetic analog of corticotropin-releasing factor (CRF) with a lactam bridge and several unnatural residues that make it stable and long-acting.

What researchers study

  • Nonselective antagonist at the CRF1 and CRF2 receptors.
  • Used to block CRF signaling in stress research.

Specifications

Molecular formulaC183H305N47O55
Molecular weight4043.7 g/mol
PubChemCID 73350132
FormLyophilized powder
Vial sizes2 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 4043.7 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.