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Dihexa

Angiotensin IV analog

A small angiotensin IV analog developed at Washington State University.

Vial size

NeuropeptidesHPLC · MS · Endotoxin

Dihexa 10 mg research vial

What it is

Dihexa is a stabilized analog of angiotensin IV: an N-hexanoyl group, tyrosine, isoleucine and an aminohexanoic amide.

What researchers study

  • Binds hepatocyte growth factor (HGF) and increases its activity at the c-Met receptor.
  • Studied in rodent models of synapse formation and cognition.

Specifications

SequenceHexanoyl-Tyr-Ile-(6)-aminohexanoic amide
Molecular formulaC27H44N4O5
Molecular weight504.7 g/mol
PubChemCID 129010512
FormLyophilized powder
Vial sizes10 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 504.7 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.