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PE-22-28

Spadin analog

A seven-residue peptide shortened from spadin.

Vial size

NeuropeptidesHPLC · MS · Endotoxin

PE-22-28 8 mg research vial

What it is

PE-22-28 is a short form of spadin, which is itself a fragment of the sortilin propeptide.

What researchers study

  • Blocks the TREK-1 potassium channel.
  • Studied in rodent models of depression-like behavior.

Specifications

SequenceGVSWGLR
Molecular formulaC35H55N11O9
Molecular weight773.9 g/mol
PubChemCID 165437303
FormLyophilized powder
Vial sizes8 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 773.9 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.