What it is
Follistatin is a glycoprotein that binds activin and other TGF-β family members, including myostatin. FST-344 is its 344-residue precursor; removing the 29-residue signal peptide gives the FST-315 isoform.
What researchers study
- Used in muscle and reproductive research as an inhibitor of activin and myostatin signaling.
Specifications
| Size | 344-residue precursor; the 315-residue isoform after the signal peptide is removed |
| Form | Lyophilized powder |
| Vial sizes | 1 mg |
| Storage | Unopened: 2 to 8 °C, away from light |
How each lot is tested
Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:
- Purity by reversed-phase HPLC: the main peak's share of the total peak area.
- Identity by mass spectrometry: the observed mass is checked against the expected mass.
- Endotoxin, measured for every lot.
The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.
The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.
Storage and handling
Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.
For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.