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P21

P021

A small peptidomimetic derived from ciliary neurotrophic factor.

Vial size

Signaling and otherHPLC · MS · Endotoxin

P21 50 mg research vial

What it is

P021 comes from the active region of ciliary neurotrophic factor (CNTF). It ends in an adamantane-based amino acid, which adds stability.

What researchers study

  • Studied in rodent models of neurogenesis, synaptic plasticity and Alzheimer-type pathology.
  • Research links its activity to BDNF expression.

Specifications

SequenceAc-DGGL-(3-aminoadamantane-1-carbonyl)-NH2
Molecular formulaC27H42N6O8
Molecular weight578.7 g/mol
PubChemCID 56589645
FormLyophilized powder
Vial sizes50 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 578.7 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.