What it is
This is Modified GRF 1-29, sold in the research market as CJC-1295 without DAC. It is the active 1–29 fragment of growth hormone-releasing hormone with four substitutions: D-Ala at position 2, Gln at 8, Ala at 15 and Leu at 27. They make it more resistant to enzymatic breakdown than native GRF 1-29.
The original CJC-1295 carries an extra lysine with a DAC group. That version is listed separately as CJC-1295 DAC.
What researchers study
- Agonist at the GHRH receptor on pituitary somatotroph cells.
- Used to study pulsatile growth hormone release, often alongside ghrelin-receptor agonists.
Specifications
| Sequence | Y-(D-Ala)-DAIFTQSYRKVLAQLSARKLLQDILSR-NH2 |
| Molecular formula | C152H252N44O42 |
| Molecular weight | 3367.9 g/mol |
| Form | Lyophilized powder |
| Vial sizes | 2 mg, 5 mg |
| Storage | Unopened: 2 to 8 °C, away from light |
How each lot is tested
Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:
- Purity by reversed-phase HPLC: the main peak's share of the total peak area.
- Identity by mass spectrometry: the observed mass should match the expected 3367.9 g/mol.
- Endotoxin, measured for every lot.
The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.
The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.
Storage and handling
Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.
For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.