Ipamorelin · Pentapeptide secretagogue

What it is

Ipamorelin is a five-residue synthetic peptide. In the 1998 animal studies that introduced it, it released growth hormone without the rise in ACTH and cortisol seen with earlier secretagogues such as GHRP-6.

What researchers study

Agonist at the ghrelin receptor, GHS-R1a.
Used as a selective tool compound in growth hormone release studies.

Specifications

Sequence	`Aib-His-D-2Nal-D-Phe-Lys-NH2`Aib is 2-aminoisobutyric acid; D-2Nal is D-3-(2-naphthyl)alanine.
Molecular formula	C₃₈H₄₉N₉O₅
Molecular weight	711.9 g/mol
PubChem	CID 9831659
Form	Lyophilized powder
Vial sizes	2 mg, 5 mg
Storage	Unopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

Purity by reversed-phase HPLC: the main peak's share of the total peak area.
Identity by mass spectrometry: the observed mass should match the expected 711.9 g/mol.
Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.