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Survodutide

BI 456906

A lipidated glucagon analog that acts on both the glucagon and GLP-1 receptors.

Vial size

Incretin analogsHPLC · MS · Endotoxin

Survodutide 10 mg research vial

What it is

Survodutide is a glucagon-based peptide with a fatty-acid side chain, described in 2022 as BI 456906. Unlike several other dual agonists, it is an analog of glucagon itself rather than of oxyntomodulin.

What researchers study

  • Dual agonist at the glucagon receptor and the GLP-1 receptor.
  • Preclinical work looks at food intake and energy expenditure in rodent obesity models.
  • Also studied in models of fatty liver disease, where glucagon signaling in the liver is a research focus.

Specifications

Molecular formulaC192H289N47O61
Molecular weight4231.6 g/mol
PubChemCID 171378821
FormLyophilized powder
Vial sizes10 mg
StorageUnopened: 2 to 8 °C, away from light

How each lot is tested

Samples from every lot go to an independent, ISO/IEC 17025 accredited lab. Its report covers three tests:

  • Purity by reversed-phase HPLC: the main peak's share of the total peak area.
  • Identity by mass spectrometry: the observed mass should match the expected 4231.6 g/mol.
  • Endotoxin, measured for every lot.

The lot number on your vial is the number on its report. How to check a certificate of analysis walks through what to look for.

The amount on the label is the weight of the powder. Besides the peptide it includes counter-ions and some water; Purity vs. peptide content explains the difference.

Storage and handling

Store unopened vials at 2 to 8 °C, away from light, as printed on the label. Let a cold vial reach room temperature before you open it, so moisture doesn't condense on the powder. More bench habits are in Handling.

For laboratory research use only. Not for human or veterinary use. This page describes the compound and published research on it. It is not a recommendation for any use.